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. Author manuscript; available in PMC: 2018 Jun 15.
Published in final edited form as: J Immunol. 2017 May 12;198(12):4855–4867. doi: 10.4049/jimmunol.1602175

Fig. 1. Integrin CD11d deficiency decreases the development of atherosclerosis and reduces macrophage foam cell formation in mice.

Fig. 1

CD11d−/−/ApoE−/− and ApoE−/− mice were fed a western diet for 16 weeks, then entire aortas (A) and aorta sinuses (B) and peritoneal macrophages (C) were isolated and stained with Oil Red O. Five slides were analyzed from each mouse. The staining was analyzed with Image-Pro Plus software. Statistical analysis was performed using Student’s t-test. (* P<0.01). D. Scavenger receptor expression was evaluated by flow cytometry on peritoneal macrophages isolated from CD11d−/−/ApoE−/− (white bars) and ApoE−/− (black bars) mice using anti-CD36, anti-SR-A1 and anti-LOX-1 antibodies. The data represent the mean + SEM from 3 mice of each group.