Table 6.
Histological grade 1 and 2 |
Histological grade 3 |
Total subjects |
|||||||
---|---|---|---|---|---|---|---|---|---|
Variables | HER-2 -tive n = 71 (%) | HER-2 +tive n = 87 (%) | P | HER-2-tive n = 28 (%) | HER-2 +tive n = 72 (%) | P | HER-2-tive n = 99 (%) | HER-2+tive n = 159 (%) | P |
KI-67* | <0.001 | 0.593 | <0.001 | ||||||
Low | 40(56.34) | 12(13.79) | 2(7.41) | 10(13.89) | 42(42.86) | 22(13.84) | |||
High | 31(43.66) | 75(86.21) | 25(92.59) | 62(86.11) | 56(57.14) | 137(86.16) | |||
ER | <0.001 | 0.531 | <0.001 | ||||||
Negative | 6(8.45) | 36(41.38) | 14(50.00) | 41(56.94) | 20(20.20) | 77(48.43) | |||
Positive | 65(91.55) | 51(58.62) | 14(50.00) | 31(43.06) | 79(79.80) | 82(51.57) | |||
PR | <0.001 | 0.451 | <0.001 | ||||||
Negative | 11(15.49) | 41(47.13) | 14(50.00) | 42(58.33) | 25(25.25) | 83(52.20) | |||
Positive | 60(84.51) | 46(52.87) | 14(50.00) | 30(41.67) | 74(74.75) | 76(47.80) | |||
P-53 | <0.001 | 0.531 | <0.001 | ||||||
Negative | 56(78.87) | 41(47.13) | 14(50.00) | 31(43.06) | 70(70.71) | 72(45.28) | |||
Positive | 15(21.13) | 46(52.87) | 14(50.00) | 41(56.94) | 29(29.29) | 87(54.72) |
No Ki-67data available for one case of patient.