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. 2017 Jan 11;8(4):383–392. doi: 10.1080/21655979.2016.1235101

Table 6.

Comparison of the expression of Ki-67, ER, PR and p53 between Her-2 positive and negative breast cancer patients.

  Histological grade 1 and 2
Histological grade 3
Total subjects
Variables HER-2 -tive n = 71 (%) HER-2 +tive n = 87 (%) P HER-2-tive n = 28 (%) HER-2 +tive n = 72 (%) P HER-2-tive n = 99 (%) HER-2+tive n = 159 (%) P
KI-67*     <0.001     0.593     <0.001
 Low 40(56.34) 12(13.79)   2(7.41) 10(13.89)   42(42.86) 22(13.84)  
 High 31(43.66) 75(86.21)   25(92.59) 62(86.11)   56(57.14) 137(86.16)  
ER     <0.001     0.531     <0.001
 Negative 6(8.45) 36(41.38)   14(50.00) 41(56.94)   20(20.20) 77(48.43)  
 Positive 65(91.55) 51(58.62)   14(50.00) 31(43.06)   79(79.80) 82(51.57)  
PR     <0.001     0.451     <0.001
 Negative 11(15.49) 41(47.13)   14(50.00) 42(58.33)   25(25.25) 83(52.20)  
 Positive 60(84.51) 46(52.87)   14(50.00) 30(41.67)   74(74.75) 76(47.80)  
P-53     <0.001     0.531     <0.001
 Negative 56(78.87) 41(47.13)   14(50.00) 31(43.06)   70(70.71) 72(45.28)  
 Positive 15(21.13) 46(52.87)   14(50.00) 41(56.94)   29(29.29) 87(54.72)  
*

No Ki-67data available for one case of patient.