Table 1.
CD1a | CD80 | CD83 | CD86 | HLA-DR | |
---|---|---|---|---|---|
Control | 24.2 ± 3.6 | 33.2 ± 6.7 | 36.9 ± 4.3 | 45.5 ± 2.3 | 59.6 ± 4.7 |
TNF-α | 83.5 ± 4.6a | 73.4 ± 7.4a | 78.8 ± 7.2a | 86.3 ± 5.4a | 91.2 ± 4.2a |
Ad-shSOCS1-DCs | 92.8 ± 4.2a,c | 88.6 ± 6.2a,c | 93.3 ± 3.8a,c | 93.6 ± 3.7a,b | 92.6 ± 3.4a,b |
Immature DCs were stimulated by Ad-shSOCS1. Percent of DCs expressing CD1a, CD80, CD83, CD86 and HLA-DR were detected using flow cytometry before and after 24 h TNF-α stimulation and analyzed by SPSS one-way ANOVA analysis.
Significant differences compared with that of the DCs control, p < 0.001;
no significant differences compared with that of the TNF-α control, p > 0.05;
significant differences compared with that of the TNF-α control or, p < 0.05.