Table 1.
Genes Previously Shown To Have Significantly Convergent Encoded Amino Acid Sequences among Echolocating Bats and Dolphins
| Gene Name (Symbol) | Gene Ontology | Sources |
|---|---|---|
| Cadherin-23 (CDH23) | Stereocilia organization and hair bundle formation | Shen et al. 2012 |
| Potassium channel, voltage gated KQT-like subfamily Q-4 (KCNQ4) | Cochlear neuronal excitability | Liu et al. 2011, 2012 |
| Otoferlin (OTOF) | Vesicle membrane fusion; mouse knockout causes deafness | Shen et al. 2012 |
| Protocadherin-15 (PCDH15) | Maintenance of normal retinal and cochlear function | Shen et al. 2012; Parker et al. 2013 |
| Deafness, autosomal recessive 59 (PJVK) | Required for proper function of auditory neurons | Davies et al. 2012 |
| Prestin (SLC26A5) | Cochlear hair cell motility and ion exchange | Li et al. 2008, 2010; Liu et al. 2010; Parker et al. 2013 |
| Transmembrane channel-like 1 (TMC1) | Required for normal functioning of cochlear hair cells | Davies et al. 2012; Parker et al. 2013 |