Table 2. Comparison of the study design and methodology for those studies included in a meta-analysis of bacterial decolonization.
Sellers and Newman 30 | May et al 25 | Guzel et al 24 | |
---|---|---|---|
Tissue type | Human umbilicus in abdominal surgery | Harvested human skin grafts | Neurosurgical operating site (cranial and spinal) |
Sample | n = 105; patients were treated as separate samples | n = 342; grafts were taken from multiple sites, yielding 3,263 samples | n = 100; patients were treated as separate samples; 50 cranial and 50 spinal patients |
Control arm | n = 70 | n = 294 (2,940 samples) | N/A |
Combination arm | n = 35 | n = 48 (323 samples) | N/A |
Application method (including timing if specified) | PVI-soaked sponge for 1 h, CHG with alcohol | CHG; alcohol; PVI | CHG 3 min; PVI 30 s; PVI 30 s |
Control antisepsis | CHG with alcohol | PVI with alcohol; PVI | Samples for culture counts were taken in between cleanings; therefore counts after CHG only are compared with CHG and PVI |
Abbreviations: CHG, chlorhexidine; DM, diabetes mellitus; N/A, not applicable; PVI, povidone-iodine.