Table 1.

Summary of ventral striatal rsFC with targeted regions of interest

Region of Interest	Subregion of Interest	Effect Size (Partial R) for Linear Age-Related Changes	Significance (p), Linear Age-Related Changes	Effect Size (Partial R) for Quadratic Age-Related Changes	Significance (p), Quadratic Age-Related Changes	Average VS-ROI timeseries correlation by age group [r]
						Children	Adolescents	Adults
Medial Prefrontal Cortex
	Subgenual Anterior Cingulate Cortex (sgACC)	−0.39	*		n.s.	0.43	0.32	0.27
	Ventral Anterior Cingulate Cortex	−0.23	††		n.s.	0.33	0.23	0.17
	Perigenual Anterior Cingulate Cortex (pgACC)	−0.22	††		n.s.	0.35	0.23	0.28
	Anterior Dorsal Anterior Cingulate Cortex (adACC)		n.s.		n.s.	0.29	0.17	0.26
	Orbitofrontal Cortex (OFC)		n.s.		n.s.	0.18	0.13	0.09
	Ventromedial Prefrontal Cortex (vmPFC)		n.s.		n.s.	0.20	0.14	0.10
Hippocampus		0.25	†		n.s.	0.03	−0.02	0.15
	Anterior Hippocampus	0.29	†		n.s.	−0.04	−0.03	0.12
	Posterior Hippocampus		n.s.	0.33	*	0.02	−0.14	0.05
Amygdala			n.s.		n.s.	0.15	0.06	0.16
Insula	Ventral Anterior Insula		n.s.	0.25	†	0.12	−0.02	0.07
	Dorsal Anterior Insula	−0.24	††	0.23	††	0.21	0.04	0.07
	Mid/Posterior Insula		n.s.	0.32	*	0.06	−0.09	0.01

Note: Effect Sizes for age-related changes derived from partial correlations conducted on parameter estimates (ß) indexing an age-connectivity relationship.

Note: Average VS-ROI timeseries correlations reflect average of single subject VS-ROI timeseries correlations per age group.

^*denotes p<.05

^†denotes p<.10, trend after Sequential Bonferroni Correction

^††denotes p<.10, n.s. after Sequential Bonferroni Correction