Table 1.
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Region of Interest | Subregion of Interest | Effect Size (Partial R) for Linear Age-Related Changes | Significance (p), Linear Age-Related Changes | Effect Size (Partial R) for Quadratic Age-Related Changes | Significance (p), Quadratic Age-Related Changes |
Average VS-ROI timeseries correlation by age group [r]
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Children | Adolescents | Adults | ||||||
Medial Prefrontal Cortex | ||||||||
Subgenual Anterior Cingulate Cortex (sgACC) | −0.39 | * | n.s. | 0.43 | 0.32 | 0.27 | ||
Ventral Anterior Cingulate Cortex | −0.23 | †† | n.s. | 0.33 | 0.23 | 0.17 | ||
Perigenual Anterior Cingulate Cortex (pgACC) | −0.22 | †† | n.s. | 0.35 | 0.23 | 0.28 | ||
Anterior Dorsal Anterior Cingulate Cortex (adACC) | n.s. | n.s. | 0.29 | 0.17 | 0.26 | |||
Orbitofrontal Cortex (OFC) | n.s. | n.s. | 0.18 | 0.13 | 0.09 | |||
Ventromedial Prefrontal Cortex (vmPFC) | n.s. | n.s. | 0.20 | 0.14 | 0.10 | |||
Hippocampus | 0.25 | † | n.s. | 0.03 | −0.02 | 0.15 | ||
Anterior Hippocampus | 0.29 | † | n.s. | −0.04 | −0.03 | 0.12 | ||
Posterior Hippocampus | n.s. | 0.33 | * | 0.02 | −0.14 | 0.05 | ||
Amygdala | n.s. | n.s. | 0.15 | 0.06 | 0.16 | |||
Insula | Ventral Anterior Insula | n.s. | 0.25 | † | 0.12 | −0.02 | 0.07 | |
Dorsal Anterior Insula | −0.24 | †† | 0.23 | †† | 0.21 | 0.04 | 0.07 | |
Mid/Posterior Insula | n.s. | 0.32 | * | 0.06 | −0.09 | 0.01 |
Note: Effect Sizes for age-related changes derived from partial correlations conducted on parameter estimates (ß) indexing an age-connectivity relationship.
Note: Average VS-ROI timeseries correlations reflect average of single subject VS-ROI timeseries correlations per age group.
denotes p<.05
denotes p<.10, trend after Sequential Bonferroni Correction
denotes p<.10, n.s. after Sequential Bonferroni Correction