Table 1.
Summary of total CMB counts and densities across all subjects by anatomic and dosimetric region. For lobar regions, density calculations are normalized to the volume of each lobe receiving at least 30 Gy (MDV30). Units of CMB density are given in CMBs/dm3
| 1-2 Years | 3-4 Years | |||
|---|---|---|---|---|
| Region | Total CMB Count | Median CMB Density (range) | Total CMB Count | Median CMB Density (range) |
| Whole Brain | 66 | 4.43 (0.68 – 12.4) | 240 | 23.0 (15.5 - 47.4) |
| <30 Gy | 2 | 0 (0–1.48) | 35 | 6.41 (2.48 – 14.6) |
| 30-45 Gy | 8 | 5.7 (0 – 14.1) | 52 | 32.9 (28.9 – 74.7) |
| >45 Gy | 56 | 9.51 (0 – 27.0) | 154 | 47.6 (24.8 – 97.6) |
| Frontal Lobe | 6 | 0 (0–6.30) | 50 | 29.1 (0.0 – 70.3) |
| Parietal Lobe | 19 | 8.27 (0–45.9) | 58 | 75.3 (26.9 – 135) |
| Occipital Lobe | 6 | 0 (0 – 38.1) | 35 | 37.9 (0 – 97.8) |
| Temporal Lobe | 9 | 5.10 (0 – 30.7) | 26 | 67.1 (0 – 318) |
| Periventricular White Matter | 26 | 7.7 (0–30.2) | 71 | 53.9 (0 – 152) |