Table 2.
Comparison of Haplotype Classification Methods for 813 Sickle Cell Anemia Patients from the CSSCD
| Haplotype | 5 RFLPs | 4 SNPs | Concordance |
|---|---|---|---|
| BEN/BEN | 371 | 367 | 0.989218329 |
| BEN/CAR | 226 | 224 | 0.991150442 |
| BEN/SEN | 91 | 91 | 1 |
| BEN/CAM | 41 | 41 | 1 |
| CAR/CAR | 31 | 31 | 1 |
| CAR/SEN | 17 | 17 | 1 |
| CAR/CAM | 14 | 14 | 1 |
| SEN/CAM | 9 | 9 | 1 |
| SEN/SEN | 8 | 8 | 1 |
| BEN/AI | 2 | 0 | 0 |
| CAR/AI | 1 | 1 | 1 |
| SEN/AI | 1 | 1 | 1 |
| CAM/CAM | 1 | 1 | 1 |
Five RFLP represents haplotypes previously assigned by RFLPs using information from 5 restriction sites based on Southern blotting. 4 SNPs represents the number of haplotypes assigned using the phased SNP-based classification