Table 1.
Descriptive characteristics of all CHS participants with incident ischemic stroke and populations eligible for survival analysis and recovery analysis
All CHS participants with incident ischemic stroke (N=893) | Eligible Survival Analysis Study Population (N=717) | Eligible Recovery Analysis Study Populations (N=509) | |
---|---|---|---|
| |||
Characteristics* | N (%) or Mean (SD) or Median [IQR] | ||
Age at time of stroke(years) | 81.8 (6.4) | 81.0 (6.4) | 80.2 (6.6) |
Sex | |||
Female | 545 (61.0%) | 434 (60.5%) | 289 (56.8%) |
Race | |||
White | 766 (85.7%) | 623 (86.9%) | 448 (88.0%) |
Black or Other | 128 (14.3%) | 94 (13.1%) | 61 (12.0%) |
Education | |||
No high school completion | 273 (30.5%) | 214 (29.9%) | 160 (31.4%) |
Completed High School | 270 (30.2%) | 215 (30.0%) | 148 (29.1%) |
Any higher education | 351 (39.3%) | 288 (40.2%) | 201 (39.5%) |
Smoking | |||
Never | 442 (49.4%) | 362 (50.5%) | 269 (52.9%) |
Former | 386 (43.2%) | 304 (42.4%) | 209 (41.1%) |
Current | 66 (7.4%) | 51 (7.1%) | 31 (6.1%) |
Alcohol Consumption | |||
None | 561 (62.8%) | 437 (61.0%) | 298 (58.3%) |
≤ 5 drinks per week | 236 (26.4%) | 196 (27.3%) | 152 (29.9%) |
> 5 drinks per week | 97 (10.9%) | 84 (11.7%) | 59 (11.6%) |
Living Arrangements | |||
Lives alone | 252 (28.2%) | 195 (27.2%) | 119 (23.4%) |
Lives with others | 518 (57.9%) | 420 (58.6%) | 318 (64.5%) |
Unknown | 124 (13.9%) | 102 (14.2%) | 72 (14.2%) |
Prior history of CHD | 260 (29.1%) | 228 (31.8%) | 163 (32.0%) |
Prior history of heart failure | 83 (9.3%) | 77 (10.7%) | 56 (11.0%) |
Atrial Fibrillation | |||
Diagnosed prior to stroke | 207 (23.2%) | 152 (21.2%) | 100 (19.7%) |
Diagnosed at stroke | 68 (7.6%) | 49 (6.8%) | 34 (6.7%) |
Depressive symptoms (CES-D≥12) | 169 (18.9%) | 140 (19.5%) | 100 (19.7%) |
Low Cognitive Function (3MSE<80) | 130 (14.7%) | 112 (15.8%) | 83 (16.5%) |
Diabetes | 287 (32.3%) | 233 (32.6%) | 178 (35%) |
BMI (kg/m2) | 26.8 (4.7) | 26.7 (4.6) | 26.7 (4.6) |
Fatal Stroke | 73 (8.2%) | 60 (8.4%) | 36 (7.1%) |
Stroke location | |||
Left hemisphere | 383 (42.8%) | 296 (41.3%) | 216 (42.5%) |
Right hemisphere | 337 (37.7%) | 271 (37.8%) | 187 (36.7%) |
Basilar | 108 (12.1%) | 93 (13.0%) | 61 (12.0%) |
Other or Unknown | 66 (7.4%) | 57 (8.0%) | 45 (8.8%) |
Ischemic Stroke Subtype | |||
Lacunar | 116 (13.0%) | 102 (14.2%) | 75 (14.7%) |
Atherosclerotic | 43 (4.8%) | 35 (4.9%) | 25 (4.9%) |
Cardio-embolic | 249 (27.9%) | 187 (26.1%) | 125 (24.6%) |
Other and unknown | 486 (54.4%) | 393 (54.8%) | 284 (55.8%) |
Anti-hypertensive med. Use | 579 (64.8%) | 469 (65.4%) | 331 (65.0%) |
Anticoagulant med. Use | 48 (5.4%) | 41 (5.7%) | 27 (5.3%) |
Frailty Status† | |||
Not Frail | 148 (27.8%) | 160 (30.1%) | 111 (28.8%) |
Pre-Frail | 292 (54.9%) | 294 (55.3%) | 217 (56.2%) |
Frail | 92 (17.3%) | 78 (14.7%) | 58 (15.0%) |
Slow Walking Speed† | 279 (44.8%) | 280 (44.9%) | 212 (46.1%) |
Low Grip Strength† | 192 (32.7%) | 192 (32.7%) | 149 (34.5%) |
C Reactive Protein (mg/dL)† | 3.0 [1.5–6.5] | 3.0 [1.5–6.5] | 2.9 [1.5–6.7] |
Interleukin-6 (pg/mL)† | 2.9 [1.9–4.3] | 2.9 [1.9–4.3] | 2.7 [1.7–4.2] |
Cystatin C (mg/dL)† | 1.1 [1.0–1.3] | 1.1 [1.0–1.3] | 1.1 [1.0–1.4] |
Systolic Blood Pressure (mmHg)† | 144 (24) | 144 (24) | 144 (25) |
Diastolic Blood Pressure (mmHg)† | 72 (12) | 72 (12) | 72 (13) |
Total Cholesterol (mg/dL)† | 208 (41) | 208 (41) | 209 (41) |
Most recently obtained measurements that occurred prior to stroke.
Measurements obtained from baseline or years 3, 7, 16 were eligible for this study