Figure 5.

CCR7 siRNA inhibits esophageal squamous carcinoma cells growth in the nude mouse xenograft model. Representative images of tumor-bearing mice (A) and tumor volume from all of the mice in each group (B). n = 6, Data is mean±SD of three independent experiments; for indicated comparisons, *P<0.05, **P<0.01. (C) Effect of CCR7 siRNA on the expression of VEGF-A, VEGF-C, TNF-α, IL-6, IL-8, TGF-β expression and NF-κB phosphorylation in the nude mouse xenograft was detected by western blotting with specific antibodies.