Skip to main content
. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Epilepsia. 2017 Jun 20;58(8):e122–e126. doi: 10.1111/epi.13826

Figure 1.

Figure 1

A. Sample EEG recordings obtained before (left) and 24 hours after (right) kindling from a saline treated rat in response to threshold stimulation. Horizontal brackets on the first part of each recording show the stimulus train and the numbers on the top of the brackets indicate the applied current. B. Only the rats of LTA group showed a decreased ADT as compared with the baseline values, LTA-A and saline groups. Neither LTA, nor LTA-A affected the ADD before rapid kindling as compared with baseline. Data are presented as Mean ± SD and are expressed as fold-changes vs. pre-kindling values. For statistical comparisons, absolute values were used. *p<0.05 vs. respective saline group (One way ANOVA followed by Tukey’s test). C. The LTA-A delayed manifestation of the Racine’s stages excluding focal seizures, #p<0.001 vs the rest of the groups. D. Treatment with LTA-A significantly reduced the number of stage 4–5 seizures during rapid kindling. However, the intracerebral administration of LTA did not affect the number of the same behavioral seizures, *p<0.001 vs Saline group. Data are presented as Mean ± SD. (One way ANOVA followed by Tukey’s test).