Table 2.
Relationship between Tumor Position and Clinicopathological Parameters in 289 Colorectal Cancer Patients.
| Clinicopathological Parameters | RSCC# (n = 57) | LSCC▴ (n = 87) | Rectal cancer (n = 145) | Total (n = 289) | P1* | P2* | P3* | P4* | P5* |
|---|---|---|---|---|---|---|---|---|---|
| Gender | 0.869 | 0.615 | 0.648 | 0.915 | 0.868 | ||||
| Male | 35 | 57 | 94 | 186 | |||||
| Female | 22 | 30 | 51 | 103 | |||||
| Age (year) | 58.6 ± 12.9 | 60.0 ± 11.7 | 59.8 ± 10.1 | 59.6 ± 11.2 | 0.743 | 0.511 | 0.484 | 0.910 | 0.775 |
| Preoperative chemotherapy | 0.845 | 0.949 | 0.691 | 0.591 | 0.565 | ||||
| No | 50 | 76 | 130 | 256 | |||||
| Yes | 7 | 11 | 15 | 33 | |||||
| Open or Laparoscopic | 0.004 | 0.003 | 0.001 | 0.885 | 0.073 | ||||
| Open | 51 | 59 | 97 | 207 | |||||
| Laparoscopic | 6 | 28 | 48 | 82 | |||||
| Gross Type | 0.598 | 0.567 | 0.318 | 0.648 | 0.394 | ||||
| Protruding | 9 | 17 | 32 | 58 | |||||
| Ulcerative & Infiltratie | 48 | 70 | 113 | 231 | |||||
| Diameter (cm) | 5.4 ± 2.3 | 4.3 ± 1.5 | 4.1 ± 1.6 | 4.4 ± 1.8 | 0.000 | 0.002 | 0.000 | 0.415 | 0.004 |
| Differentiation | 0.000 | 0.000 | 0.000 | 0.363 | 0.066 | ||||
| Well & Moderate | 33 | 78 | 124 | 235 | |||||
| Poor☆ | 24 | 9 | 21 | 54 | |||||
| T | 0.000 | 0.110 | 0.000 | 0.015 | 0.000 | ||||
| T1-T2 | 5 | 16 | 48 | 69 | |||||
| T3-T4 | 52 | 71 | 97 | 220 | |||||
| N | 0.708 | 0.437 | 0.466 | 0.891 | 0.772 | ||||
| N0 | 29 | 50 | 82 | 161 | |||||
| N1-N2 | 28 | 37 | 63 | 128 | |||||
| M | 0.667 | 0.980 | 0.502 | 0.423 | 0.368 | ||||
| M0 | 44 | 67 | 118 | 229 | |||||
| M1 | 13 | 20 | 27 | 60 | |||||
| TNM | 0.011 | 0.711 | 0.008 | 0.042 | 0.001 | ||||
| 1 | 5 | 12 | 43 | 60 | |||||
| 2 | 22 | 27 | 33 | 82 | |||||
| 3 | 17 | 28 | 44 | 89 | |||||
| 4 | 13 | 20 | 25 | 58 | |||||
| CEA (ng/mL) | 0.590 | 0.951 | 0.473 | 0.273 | 0.259 | ||||
| Unknown | 3 | 5 | 3 | 11 | |||||
| <5 | 31 | 45 | 84 | 160 | |||||
| >=5 | 23 | 37 | 58 | 118 | |||||
| CA199 (U/mL) | 0.298 | 0.439 | 0.142 | 0.297 | 0.200 | ||||
| Unknown | 4 | 5 | 3 | 12 | |||||
| <37 | 40 | 69 | 116 | 225 | |||||
| >=37 | 13 | 13 | 26 | 52 | |||||
| Tumor Deposit | 0.207 | 0.677 | 0.311 | 0.094 | 0.083 | ||||
| No | 47 | 74 | 110 | 231 | |||||
| Yes | 10 | 13 | 35 | 58 | |||||
| Perineural Invasion | 0.643 | 0.967 | 0.505 | 0.410 | 0.348 | ||||
| No | 49 | 75 | 119 | 243 | |||||
| Yes | 8 | 12 | 26 | 46 | |||||
| Vascular Invasion | 0.454 | 0.493 | 0.757 | 0.213 | 0.305 | ||||
| No | 49 | 71 | 127 | 247 | |||||
| Yes | 8 | 16 | 18 | 42 |
#RSCC: Right-sided colon cancer; ▴LSCC: Left-sided colon cancer; *P1: comparison of three group; P2: RSCC vs. LSCC; P3: RSCC vs. rectal; P4: LSCC vs. rectal; P5:colon vs. rectal; ☆Poorly differentiated, Mucinous adenocarcinoma, signet ring cell carcinoma.