Table 2.

Independent Predictors of Percent Change in eGFR at 1-Year Follow-up.

Predictors	Effect estimate (% change in eGFR) (95% CI)	Odds Ratio (95% CI)	P-value
High sCD40L	−7.57 (−13.60, −1.54)	1.89 (1.13, 3.10)	0.014
Low sCD40R	−6.39 (−12.59, −0.18)	1.71 (1.01, 2.85)	0.044
Systolic BP	−0.20 (−0.36, −0.04)	1.02 (1.00, 1.03)	0.02

Model was adjusted by age, sex, baseline eGFR, systolic blood pressure (SBP), peripheral vascular disease (PVD), diabetes mellitus, primary renal disease, and baseline ACEi/ARB or aspirin use. Odds ratios were calculated for a negative percent change in eGFR at 1-year follow-up. Only significant predictors are shown.

Abbreviations: eGFR, estimated glomerular filtration rate; sCD40L, soluble CD40 ligand; sCD40R, soluble CD40 receptor; BP, blood pressure; and CI, confidence interval.