Fig. 13.

CK2 catalytic activity is inhibited by short-term exposure to specific inhibitors: Cell lysates were generated from a Calu-3 cells treated with TBB (10 μM; 5 min) or CX4945 (10 μM; 5 min) or b HEK-293T cells treated with CX4945 (10 μM; 5 min) or the αCK2-KO HEK-293T and CK2 activity was determined by means of radioactive assays with [γ-33P]ATP towards the specific CK2 substrate peptide CK2-tide (RRRADDSDDDDD).***Significant effect of inhibitor vs. untreated control or αCK2KO vs. control (p < 0.001). Data represents mean ± S.E.M., n = 4