Table 3.
Outcomes of filter efficiency in 10 procedures
| Parameter (n = 10) | C max (µg/ml) | AUC (h.mg/L) | Filter efficiencya | Filter efficiency at time T x (%)b | ||||
|---|---|---|---|---|---|---|---|---|
| Pre-filter | Post-filter | Overall | T c10 | T cend infusion | T cend washout | Mean | ||
| Mean | 1.13 | 4.29 | 0.57 | 86.0 | 95.4 | 85.9 | 77.5 | 86.3 |
| SEM | 0.13 | 0.28 | 0.0 | 2.5 | 2.1 | 3.6 | 8.1 | 3.7 |
| Median | 1.15 | 4.55 | 0.49 | 87.2 | 100 | 86.3 | 84.4 | 86.2 |
| Minimum | 0.50 | 2.20 | 0.23 | 71.1 | 82.7 | 63.6 | 30.0 | 68.2 |
| Maximum | 1.80 | 5.20 | 1.30 | 95.5 | 100 | 100 | 100 | 100 |
| Range | 1.30 | 3.00 | 1.07 | 24.4 | 17.2 | 36.4 | 70 | 31.8 |
SEM standard error of the mean
a[(AUCpre-filter − AUCpost-filter)/AUCpre-filter] × 100
b[(Pre-filter concentration) − (post-filter concentration)/(pre-filter concentration)] at time T x
ct10 versus t30: p = 0.013; t30 versus t60: p = 0.290; t10 versus t60: p = 0.051. (p for significance is p < 0.017)