Table 2.
Demographic data and baseline parameters before therapy or when first presenting at our institution
| Patient ID | m/f | Agea | Side | Initial symptoms | 4PTA (dB HL) |
WRS65dB
(%) |
WRSmax
(%) |
4PTA contral. (dB HL) |
Calorics DP (%) |
vHIT gain (anterior; lateral; posterior) |
cVEMP AR |
oVEMP AR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | m | 38 | R | Sudden hearing loss and vertigo | 71 | 0 | 0 | 53.2 | – | – | – | – |
| 2 | m | 39 | R | Provocational nystagmus, later low-frequency hearing loss and tinnitus |
>110 | 0 | 0 | 21.25 | – | – | 0.92 | 0.81 |
| 3 | m | 49 | L | 1998: posttraumatic deafness contralateral, 10/2010: sudden hearing loss left followed by fluctuating hearing loss; HA left; tinnitus R > L, no vertigo/dizziness |
108.75 | 0 | 0 | >110 | 34.7 | – | – | – |
| 4 | m | 44 | R | Tinnitus, progressive hearing loss, pressure sensation/fullness | 75 | 0 | 25 | 16.25 | 0 | – | – | – |
| 5 | m | 43 | L | Progressive hearing loss, tinnitus | 54 | 30 | 80 | 5 | – | – | – | – |
| 6 | f | 50 | R | Sudden hearing loss with deafness | >110 | 0 | 0 | 17.5 | – | –, 0.70, – |
– | – |
| 7 | f | 60 | R | Since 2011 progressive hearing loss (recurrent episodes of sudden hearing loss), 8/2013 deafness, episodic vertigo for approximately 24 h, tinnitus | >110 | 0 | 0 | 7.5 | 32.1 | – | – | – |
| 8 | f | 25 | R | 10/2014: sudden hearing loss; tinnitus; attacks of spinning vertigo, 3–4 x per day | 55 | 5 | 80 | 8.75 | 32.8 | 0.46; 0.68; 0.65 | 0.35 | 0.69 |
| 9 | f | 37 | R | 2005: sudden hearing loss; postural instability, progressive hearing loss to deafness (2015) | >110 | 0 | 0 | 6.25 | 3.6 | 0.92; 0.99; 0.85 | 0.69 | n.a. |
| 10 | m | 51 | R | Sudden deafness 21 years ago, MRI at that time described as normal, tinnitus R > L | >110 | 0 | 0 | 8.75 | 24.1 | 0.42; 0.55; 0.46 | – | – |
| 11 | f | 59 | R | 1994: stapedoplasty ipsilateral, 1994 MRI described as normal; progressive hearing loss, HA, history of breast cancer | 111.25 | 0 | 15 | 10 | only warm irrigation tolerated | 0.43; 1.17; 0.66 | – | – |
| 12 | f | 65 | R | Hearing loss bilateral since 1988, since 1992 HAs, since 2015 HAs insufficient | 93.75 | 0 | 0 | >110 | 7.7 | not possible (ocular episthesison vHIT camera side) | 0.32 | 0.34 |
| Σ | 6 f 6 m |
47 ± 10 | 10 R 2 L |
– | – | – | – | – | – | – | – | – |
m/f Male/female, AR asymmetry ratio, R right, L left, DP directional preponderance, – no measurement done, HA(s) hearing aid(s), 4PTA pure-tone average at 0.5, 1, 2, 4 kHz, WRS 65dB/max (word recognition score): percent of monosyllables (Freiburger test in quiet) understood at 65 dB sound pressure level (SPL) or maximally reached at an optimal stimulation level, vHIT video head impulse test, VEMP ocular (o) or cervical (c) vestibular evoked myogenic potentials, deafness refers to profound hearing loss or anacusis (no measurable threshold)
aAge in years at initial diagnosis by MRI (mean ± standard deviation)