Table 2.
Distribution of CSE, CBS and 3‐MPST in the GI tract
| Species | Organ | Enzyme | Cell type/layer | Method | References |
|---|---|---|---|---|---|
| Mouse | Stomach | CBS/CSE | SMC | IHC/WB | Han et al., 2011 Huang et al., 2013 |
| Small intestine | CBS/CSE | SMC (tunica muscularis) | WB | Guo et al., 2012 | |
| Colon | CBS | Lamina propia | RT‐PCR/IHC | Linden et al., 2008 | |
| CSE | MP (lamina propia and SMC diffuse) | ||||
| Guinea Pig | Ileum and Colon | CBS | MP,SMC | IHC | Schicho et al., 2006 |
| CSE | MP, SMP, ICC | ||||
| Human | Colon | CBS/CSE | SMP | IHC | Schicho et al., 2006 |
| CBS/CSE | Epithelium | WB | Martin et al., 2010 | ||
| Rat | Stomach | CBS/CSE | Epithelium (mucosa) | RT‐PCR | Fiorucci et al., 2005 |
| Jejunum | CBS/CSE | MP | IHC | Kasparek et al., 2012 | |
| Colon | CBS/CSE | Epithelium, SMC | IHC | Hennig and Diener, 2009 | |
| CBS | Muscularis mucosa, SMP, lamina propia | IHC/WB | Martin et al., 2010 | ||
| CSE | General diffuse | ||||
| CBS | Epithelium, SMC (diffuse) | IHC | Gil et al., 2011 | ||
| CSE | MP, SMP, SMC (mucosa and submucosa diffuse) | ||||
| CBS | MP, epithelium (SMC diffuse) | IHC | Liu et al., 2013 | ||
| CSE | MP, SMC (mucosa and submucosa diffuse) | ||||
| Rabbit | Stomach | CSE/3‐MPST | SMC | RT‐PCR/WB | Nalli et al., 2015 |
Enzymes: CSE, 3‐MPST. Techniques: IHC, immunohistochemistry; RT‐PCR; WB, Western blot. Cells/layers: SMC, MP, SMP, ICC.