Table 5.
Study | Reference (country) | Year of study | No. isolates | Testing method | Interpretation | Phenotypic resistance |
---|---|---|---|---|---|---|
1 | (34) (United States)a | 1998–1992 | 92 | Disk diffusionb | NCCLS M31-A2 (2002) | PEN (92.4%), AMP (5.4%), CEF (0%), CN (1.1%), AK (0%), SPC (73.9%), ERY (100%), CLD (100%), TE (93.5%), SDX (85.4%), SXT (0.9%), ENR (1.3%) |
2 | (52) (United States) | 2006–2011 | 84 | Broth microdilution | CLSI M31-A2 (2002) | PEN (70.0% R), AMX (36.0% R; 21.0% I), CEF (3.0% R; 7.0% I), S (21.0% R; 4.0% I), NEO (14.0% R; 22.0% I), CN (4.0% R; 3.0% I), NOV (100% R), ERY (43.0% R; 57.0% I), TYL (100% R), CLD (97.0% R), SPC (0% R; 89.0% I), FFN (3.0% R; 11.0% I), TE (90.0% R; 3.0% I), OTC (83.0% R; 3.0% I), STZ (8.0% R; 10.0% I), SDX (43.0% R; 14.0% I), SXT (3.0% R; 14.0% I), ENR (4.0% R; 3.0% I) |
In studies where intermediate susceptibility is given, results are presented as: R, fully resistant; I, intermediate resistant.
CLSI, Clinical Laboratory Standard Institute; NCCLS, National Committee for Clinical Laboratory Standards; AK, amikacin; AMP, ampicillin; AMX, amoxicillin; CEF, ceftiofur; CLD, clindamycin; CN, gentamicin; ENR, enrofloxacin; ERY, erythromycin; FFN, florfenicol; NEO, neomycin; NOV, novobiocin; OTC, oxytetracycline; PEN, penicillin; S, streptomycin; SDX, sulfadimethoxine; SPC, spectinomycin; STZ, sulfathiazole; SXT, co-trimoxazole; TE, tetracycline; TYL, tylosin.
aStrains identified as M. haemolytica.
bMIC distributions reported;.disk concentrations reported.