Table 2.
ALL PATIENTS AND NCS | ||||||
---|---|---|---|---|---|---|
ΔCt vs. IQ | ΔCt vs. YGTSS | ΔCt vs. ADOS Communication | ΔCt vs. ADOS Social interaction | ΔCt vs. ADOS Imagination | ΔCt vs. ADOS Repetitive and restricted behaviors | |
Spearman r | 0.02 | 0.33 | −0.13 | −0.07 | −0.17 | NT |
Pearson r | NT | NT | NT | NT | NT | −0.17 |
95% CI | −0.18–0.21 | 0.15–0.50 | −0.32–0.07 | −0.27–0.12 | −0.36–0.03 | −0.35–0.02 |
two-sided p-value | 0.86 | 0.0005 | 0.18 | 0.45 | 0.09 | 0.08 |
Is p < Bonferroni corrected α? | N | Y | N | N | N | N |
Bonferroni-Holm adjusted p-value | 1.00 | 0.008 | 1.00 | 1.00 | 1.00 | 1.00 |
Benjamini-Hochberg p-value (FDR 1%) | 0.86 | 0.008 | 0.29 | 0.51 | 0.23 | 0.23 |
Number of XY Pairs | 104 | 104 | 104 | 104 | 104 | 104 |
ASD PATIENTS AND NCS | ||||||
ΔCt vs. ADOS Communication | ΔCt vs. ADOS Social interaction | ΔCt vs. ADOS Imagination | ΔCt vs. ADOS Repetitive and restricted behaviors | |||
Spearman r | -0.27 | -0.20 | -0.31 | NT | ||
Pearson r | NT | NT | NT | -0.29 | ||
95% CI | −0.51–0.003 | −0.45–0.08 | −0.53–−0.04 | −0.51–−0.02 | ||
two-sided p-value | 0.05 | 0.15 | 0.02 | 0.03 | ||
Is p < Bonferroni corrected α? | N | N | N | N | ||
Bonferroni-Holm adjusted p-value | 0.60 | 1.00 | 0.34 | 0.47 | ||
Benjamini-Hochberg p-value (FDR 1%) | 0.18 | 0.29 | 0.18 | 0.18 | ||
Number of XY Pairs | 55 | 55 | 55 | 55 | ||
TS PATIENTS AND NCS | ||||||
ΔCt vs. YGTSS | ||||||
Spearman r | −0.03 | |||||
95% CI | −0.31–0.26 | |||||
two-sided p-value | 0.84 | |||||
Is p < Bonferroni corrected α? | N | |||||
Bonferroni-Holm adjusted p-value | 1.00 | |||||
Benjamini-Hochberg p-value (FDR 1%) | 0.86 | |||||
Number of XY Pairs | 49 | |||||
TS+ASD PATIENTS AND NCS | ||||||
ΔCt vs. YGTSS | ΔCt vs. ADOS Communication | ΔCt vs. ADOS Social interaction | ΔCt vs. ADOS Imagination | ΔCt vs. ADOS Repetitive and restricted behaviors | ||
Spearman r | 0.21 | 0.17 | 0.15 | 0.17 | 0.20 | |
95% CI | −0.08–0.47 | −0.12–0.43 | −0.14–0.42 | −0.12–0.44 | −0.09–0.46 | |
two-sided p-value | 0.14 | 0.24 | 0.28 | 0.23 | 0.17 | |
Is p < Bonferroni corrected α? | N | N | N | N | N | |
TS+ASD PATIENTS AND NCS | ||||||
ΔCt vs. YGTSS | ΔCt vs. ADOS Communication | ΔCt vs. ADOS Social interaction | ΔCt vs. ADOS Imagination | ΔCt vs. ADOS Repetitive and restricted behaviors | ||
Bonferroni-Holm adjusted p-value | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
Benjamini-Hochberg p-value (FDR 1%) | 0.29 | 0.33 | 0.35 | 0.33 | 0.29 | |
Number of XY Pairs | 50 | 50 | 50 | 50 | 50 |
We performed the analyses in both a general (Section 1) and a class-specific (Sections 2–4) manner. Either Pearson or Spearman r values from every analysis are reported. Bonferroni corrected α = 0.05/16 = 0.003. IQ, Intelligence Quotient; ADOS, Autism Diagnostic Observation Schedule; YGTSS, Yale Global Tic Severity Scale; 95% CI, 95% Confidence Interval; NT, Not Tested; N, no; Y, yes; FDR, False Discovery Rate.