Table 1.
Patient’s clinical characteristics
| Characteristics | Total case (N=13) |
|---|---|
| Male gender, n (%) | 10 (76.9%) |
| Caucasian, n (%) | 13 (100.0%) |
| Weight at the time of FMT, kg | 72.2 ± 10.9 |
| BMI at the time of FMT, kg/m2 | 24.0 ± 3.6 |
| Ever smoked, n (%) | |
| Current | 1 (7.7%) |
| Quit | 3 (23.1%) |
| Significant comorbidities, n (%) | 2 (15.4%) |
| Concurrent autoimmune disorders, n (%) | 1 (7.1%) |
| Family history of IBD, n (%) | 4 (30.8%) |
| Family history of colorectal cancer, n (%) | 2 (15.4%) |
| Age at IBD diagnosis, years | 21.7 ± 12.5 |
| Precolectomy diagnosis of UC, n (%) | 13 (100.0%) |
| Extensive colitis, n (%) | 13 (100.0%) |
| Primary sclerosing cholangitis, n (%) | 1 (7.7 %) |
| Other extra-intestinal manifestation, n (%) | 2 (15.4%) |
| Preoperative use of biologics, n (%) | 4 (30.8%) |
| Age at colectomy, years | 32.7 ± 12.6 |
| Duration from IBD diagnosis to colectomy, years | 11.0 ± 11.9 |
| Indication for colectomy, n (%) | |
| Refractory disease | 11 (84.6%) |
| Neoplasia | 2 (15.4%) |
| Stage of pouch construction, n (%) | |
| 1 | 2 (15.4%) |
| 2 | 2 (15.4%) |
| 3 | 8 (61.5%) |
| Redo pouch | 1 (7.7%) |
| J configuration of the pouch, n (%) | 13 (100.0%) |
| Postoperative leak/abscess, n (%) | 5 (38.5%) |
| Concurrent stricture, n (%) | 7 (53.8%) |
| Concurrent cuffitis, n (%) | 5 (38.5%) |
| Concurrent CD of pouch, n (%) | 4 (30.8%) |
| Age at the diagnosis of CDI, years | 44.5 ± 13.8 |
| Duration from colectomy to diagnosis of CDI, years | 11.5 ± 6.9 |
| Presenting symptoms, n (%) | |
| Increase bowel movements | 8 (61.6%) |
| Urgency | 10 (76.9%) |
| Abdominal pain | 8 (61.5%) |
| Nausea and vomiting | 3 (23.1%) |
| Bleeding, n (%) | 2 (15.4%) |
| Mean session of FMT, n (%) | 1.7 ± 1.1 |
| Route of FMT, n (%) | |
| Pouchoscopy | 16 (72.7%) |
| Esophagogastroduodenoscopy | 4 (18.2%) |
| Self-enema | 2 (9.1%) |
| Volume of stool administered, ml | 186.9 ± 70.6 |
| Pouchoscopy | |
| Upper endoscopy | 30.0 ± 0.0 |
| Duration of follow-up, years | 1.2 ± 1.1 |
| Hospitalization after FMT treatment, n (%) | 2 (15.4%) |
| Cause of diverted pouch, n (%) | |
| Nausea and abdominal pain | 2 (15.4%) |
| Bowel obstruction | 1 (7.7%) |
| Ischemic pouchitis | 1 (7.7%) |
CDI, Clostridium difficile infection; FTM, fecal microbiota transplant; IBD, inflammatory bowel disease.