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. 2017 Aug 12;17:401. doi: 10.1186/s12906-017-1909-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Effects of Chinese herbal extracts (CHE) on the expression levels of migratory proteins using MDA-MB-231 cells. Cultured MDA-MB-231 cells without/with a CHE (1 μg/mL for each herbal extract) pretreatment were lysed and the expression levels of various proteins related to migration, namely Rac 1/2/3, CDC42, Rho (a) and COX2, MMP2 and MMP9 (b) were analyzed by Western blot. A similar process was carried out for two angiogenesis related proteins, namely VEGFA and VEGFR2 (c) The results are expressed as mean + SEM. *, p < 0.05 compared to the vehicle group by repeatedly measured one way ANOVA; #, p < 0.05 by Student’s t test (n = three to five independent experiments in each group)