Fig. 4.

—Comparison of variable bla_NDM-1-containing regions from plasmids p16Pre36-NDM, pRB151-NDM, p06-1619-NDM, p6234-178kb, pPrY2001 and pNDM-BJ01. Insertion sequences or transposons are shown as rectangles containing their respective CDS for transposition and accessory genes in different colors. Outside orange and green triangles correspond to the inverted repeats of a putative Tn3-like (Tn6369) and a Tn21, respectively. The prototype sequence of the Tn21 was included (Liebert et al. 1999). Dashed lines indicate the 2,928-bp sequence containing ISVsa3 carried by p6234.178kb (once) and p16Pre36-NDM (twice). Gray and red (inverted matches) shading between pairs of sequences indicates >90% of nucleotide identity in a window of 400 bp. The scale bar indicates sequence length.