Table 2.

Comparison of C. hepaticus with C. jejuni (reference) genomes using RAST.

RAST subsystems	HV-10	S10-0209	S11-010	S11-0036	S11-0038	S11-0069	S11-0071	S11-5013	S12-0322	S12-1018	Cj-M1	Cj-11168	Cj-PT14	Cj-R14	Cj-4031	Ave S	Ave R	t-test
Genome size (bp)	1482384	1549703	1596485	1498189	1501926	1490652	1516789	1551049	1538297	1530280	1616648	1641481	1635301	1795858	1669329	1530374	1671723	0.00
No. of genes	1512	1581	1629	1509	1511	1509	1513	1580	1531	1575	1610	1642	1631	1900	1677	1549	1692	0.01
No. of RNAs	46	42	44	44	45	44	47	44	45	44	53	53	50	53	53	44	52.4	0.00
CG content	27.9	28.5	28.5	28.4	28.4	28.1	28.5	28.5	28.4	28.2	30.6	30.5	30.5	30.4	30.5	28	30.5	0.00
Subsystem feature counts
Cofactors, vitamins, prosthetic groups, pigments	145	145	145	146	146	147	146	145	146	145	134	133	141	142	133	146	136.6	0.00
Cell wall and capsule	99	101	98	101	102	97	101	98	95	97	85	118	111	117	114	99	109	0.05
Virulence, disease, and defense	39	38	43	38	38	39	39	38	42	38	89	67	69	67	67	39	71.8	0.00
Potassium metabolism	8	8	8	8	8	8	8	8	8	8	12	13	12	13	12	8	12.4	0.00
Miscellaneous	4	4	4	4	4	4	4	5	4	4	4	4	4	4	4	4	4	0.48
Phages, prophages, transposons, plasmids	0	7	7	3	3	3	2	7	2	7	0	0	0	13	0	5	2.6	0.38
Membrane transport	47	48	59	48	48	48	48	48	66	48	41	45	45	49	40	51	44	0.05
Iron acquisition and metabolism	5	5	5	5	5	5	5	5	5	5	45	50	50	41	46	5	46.4	0.00
RNA metabolism	68	68	68	68	68	68	68	68	68	68	70	71	70	70	71	68	70.4	0.00
Nucleosides and nucleotides	48	47	47	47	47	48	47	47	47	47	50	50	50	50	50	47	50	0.00
Protein metabolism	212	210	211	211	211	210	210	210	213	210	215	215	214	214	215	211	214.6	0.00
Cell division and cell cycle	9	9	10	9	9	9	9	9	10	9	22	22	22	22	22	9	22	0.00
Motility and chemotaxis	81	83	83	81	81	83	82	83	82	83	83	85	84	85	84	82	84.2	0.00
Regulation and cell signaling	20	20	21	21	20	20	20	21	21	20	20	17	17	20	20	20	18.8	0.02
DNA metabolism	40	41	46	42	40	42	42	41	47	41	50	52	52	50	50	42	50.8	0.00
Fatty acids, lipids, and isoprenoids	71	79	79	72	72	72	72	79	69	79	63	64	64	77	69	75	67.4	0.02
Nitrogen metabolism	14	17	17	14	14	13	13	17	14	17	12	13	14	13	12	15	12.8	0.02
Respiration	78	77	77	77	77	77	77	77	80	77	72	71	72	72	73	77	72	0.00
Stress response	36	36	36	36	36	36	36	36	36	36	41	43	43	43	43	36	42.6	0.00
Amino acids and derivatives	245	251	251	244	244	241	241	251	241	251	280	286	284	293	284	246	285.4	0.00
Carbohydrates	83	112	112	84	84	86	86	112	82	112	62	62	62	75	68	97	65.8	0.00

C. hepaticus isolates: draft Australian C. hepaticus genome HV10. UK isolates: S10-0209, S11-010, S11-0036, S11-0038, S11-5013, S12-0322, and S12-1018. Reference genomes: C. jejuni NCTC 11168, M1, PT14, R14, and 4031.