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. 2017 Aug 11;11:419. doi: 10.3389/fnins.2017.00419

Table 2.

List of selected postmortem human studies examining morphological changes on dendrites of cortical pyramidal neuron including PFC.

Areas examined Pathology Age Subject numbers, diagnosis References
Frontal cortex Parietal cortex Temporal cortex ASD 12, 27 years 4 ASD Williams et al., 1980
Prefrontal cortex (BA 9) Temporal cortex (BA 21) Parietal cortex (BA 7) ASD 10–45 years 10 ASD 15 controls Hutsler and Zhang, 2010
Prefrontal (BA 10) Frontal (BA 4) Temporal (BA 21) RTT 16–24 years 2 RTT 11 TRPE 6 controls Belichenko et al., 1994
Frontal cortex Temporal cortex Occipital cortex RTT/DS 6–35 years 16 RTT 6 DS 9 controls Armstrong et al., 1998
Prefrontal (BA 9) DS Newborn, 2.5 month 2 DS 2 controls Vukšić et al., 2002
Temporal pole (BA 38) Temporal cortex (BA 22/21) Schizophrenia Adult 13 schizophrenia 1 schizophrenia-like psychosis 11 controls Garey et al., 1998
Frontal cortex (BA 46) Occipital cortex (BA 17) Schizophrenia Adult 15 schizophrenia 15 non-schizophrenia with psychiatric illness 15 controls Glantz and Lewis, 2000
Mesial frontal lobe Temporal lobe Epilepsy Not reported 14 Vaquero et al., 1982
Motor cortex (BA 4) PFC (BA 10) Broca's area (BA 44) Callosotomy Adult 2 callosotomy Jacobs et al., 2003

ASD, autism spectrum disorder; RTT, Rett syndrome; DS, Down syndrome; TRPE, therapy resistant partial epilepsy.