Figure 2.

Apigenin attenuates LPS-induced cardiac cell death. (a) TUNEL staining performed on paraffin section of mice heart in each group and representative fluorescent images were provided. Green color demonstrated TUNEL-positive nuclei. Scale bar was provided in representative Apig + LPS image. (b) Cardiac cell death markers DNA fragmentation and PARP activity assay were examined. Both DNA fragmentation and PARP activity were significantly increased in LPS-treated mice, and apigenin treatment ameliorated those elevated level. Values represented as means ± SD; ^∗P < 0.05 and n = 6/group.