Table 2.
Potential biomarkers to discriminate healthy from dengue patients.
| AUC | 95% CI | P value | Cutoff | Sensitivity % | Specificity % | |
|---|---|---|---|---|---|---|
| IL-10 | 0.9683 | 0.9222–1.014 | 0.0001 | >63.25 pg/ml | 90.48 | 100 |
| IL-6 | 0.9730 | 0.9311–1.015 | 0.0001 | >67.77 pg/ml | 95.24 | 100 |
| Platelets | 0.9742 | 0.9362–1.012 | 0.0001 | <13.6 × 104/mm3 | 93.75 | 100 |
| Albumin | 0.7594 | 0.5743–0.9245 | 0.0128 | <3.55 UI/ml | 78.38 | 63.64 |
| ALT | 0.9315 | 0.8263–1.037 | 0.0001 | >42.5 UI/ml | 83.33 | 100 |
| AST | 0.9167 | 0.8008–1.032 | 0.0001 | >31.5 UI/ml | 88.89 | 93.75 |
AUC analysis was done to identify parameters that can discriminate between healthy and sick dengue-infected patients. Sensitivity and specificity values are calculated on the base of the cutoff of each tested parameter.