Table 3.

Potential biomarkers to identify severity of dengue infection.

	AUC	95% CI	P value	Cutoff	Sensitivity %	Specificity %
IL-10	0.8519	0.6922–1.011	0.0046	>134 pg/ml	77.78	86.67
IL-6	0.5266	0.3120–0.7412	0.8177	<136.8 pg/ml	100	17.39
Platelets	0.5316	0.3400–0.7231	0.7607	<9.05 × 104/ml	100	15.79
Albumin	0.7976	0.6942–0.9461	0.0079	<3.55 UI/ml	88.89	57.14
ALT	0.9111	0.7682–1.054	0.0284	>93.5 UI/ml	100	86.67
AST	0.8000	0.5367–1.063	0.1098	> 140 UI/ml	86.67	66.67
socs1	0.8441	0.7006–0.9877	0.0069	< 1.94-fold	85.71	72.73
socs3	0.9026	0.7777–1.028	0.0016	>199.8-fold	85.71	86.36

AUC analysis was done to explore the potential of each parameter to predict dengue severity by comparing between DF and DHF patients. socs3, socs1, IL-10, and ALT have the best predictive values.