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IL-22 inhibited the PMVEC apoptosis induced by AngII. Flow cytometry revealed the apoptosis rate of PMVECs in the IL-22 group was obviously decreased compared with that of the AngII group, whereas the apoptosis rate of PMVECs in the AngII + IL-22 + AG490 group was remarkably increased compared with that of the AngII + IL-22 group.
