Table 2.

Multivariable linear regression models demonstrating associations between retinal structure and medial temporal lobe volumes among neurologically normal older adults (n = 79)

Outcome: medial temporal lobe volume
Variable	β	b	95% CI
Retinal nerve fiber layer (RNFL) thickness (µm)
Age	−0.30	−93.2	−159.0, −27.4
Sex	−0.11	−352.3	−1252.7, 548.1
TIV	0.50	0.005	0.002, 0.008
RNFL Thickness	0.31	39.3	11.9, 66.8
Model adj. R2 = 0.34
Total macular volume (mm3)
Age	−0.24	−76.9	−144.6, −9.1
Sex	0.05	172.7	−809.9, 1155.3
TIV	0.57	0.006	0.003, 0.009
Macular volume	0.23	3013.6	59.4, 5967.8
Model adj. R2 = 0.31
Macular ganglion volume (mm3)
Age	−0.20	−65.1	−133.4, 3.4
Sex	0.02	61.2	−889.6, 1012.1
TIV	0.57	0.005	0.003, 0.009
Macular ganglion volume	0.30	12,590.4	3249.4, 21,931.5
Model adj. R2 = 0.33

Key: adj., adjusted; TIV, total intracranial volume.