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Parameter settings influence on ACO-HPPFP-3 performance in 2D and 3D: ant colony size and maximum number of non-improving local search steps. Mean CPU time required for finding minimum energy conformations of Sequence S1-7 in 2D (length 60, left side) and Sequence S2-5 in 3D (length 48, right side), as a function of ant colony size and the maximum number of non-improving local search steps.
