Table 6.
ANA profile | Histological classification of lupus nephritis | P value | ||||
---|---|---|---|---|---|---|
Class II | Class III | Class IV | Class V | Class VI | ||
(N = 9) | (N = 16) | (N = 12) | (N = 1) | (N = 3) | ||
Anti RNP/Sm antibodies | 1 (11.1%) | 2 (12.5%) | 5 (41.7%) | 0 (0%) | 0 (0%) | 0.23 |
Anti Sm antibodies | 1 (11.1%) | 1 (6.25%) | 5 (41.7%) | 0 (0%) | 0 (0%) | 0.11 |
Anti SS-A antibodies | 1 (11.14%) | 6 (37.5%) | 2 (16.7%) | 0 (0%) | 1 (33.3%) | 0.53 |
Anti RO52 antibodies | 2 (22.2%) | 8 (50%) | 5 (41.7%) | 0 (0%) | 1 (3.3%) | 0.63 |
Anti SS-B antibodies | 0 (0%) | 3 (18.75%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.28 |
Anti PM-Scl antibodies | 0 (0%) | 0 (0%) | 1 (8.3%) | 0 (0%) | 0 (0%) | 0.65 |
Anti PCNA antibodies | 1 (11.1%) | 0 (0%) | 1 (8.3%) | 0 (0%) | 0 (0%) | 0.72 |
Anti dsDNA antibodies | 5 (55.6%) | 7 (43.75%) | 9 (75%) | 1 (100%) | 0 (0%) | 0.13 |
Anti-Nucleosomes antibodies | 0 (0%) | 3 (18.75%) | 8 (66.7%) | 0 (0%) | 0 (0%) | 0.005* |
Anti-Histones antibodies | 0 (0%) | 2 (12.5%) | 4 (33.3%) | 0 (0%) | 1 (33.3%) | 0.29 |
Anti† RP-protein antibodies | 0 (0%) | 2 (12.5%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.51 |
Anti AMA-M2 antibodies | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (33.3%) | 0.011* |
Ribosomal-P-Protein. No patients with lupus nephritis had a positive anti Scl-70, JO1 or Centromere B antibodies