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. 2017 Jun 14;27:114. doi: 10.11604/pamj.2017.27.114.5981

Table 6.

ANA profile distribution along the various histological classes of lupus nephritis

ANA profile Histological classification of lupus nephritis P value
Class II Class III Class IV Class V Class VI
(N = 9) (N = 16) (N = 12) (N = 1) (N = 3)
Anti RNP/Sm antibodies 1 (11.1%) 2 (12.5%) 5 (41.7%) 0 (0%) 0 (0%) 0.23
Anti Sm antibodies 1 (11.1%) 1 (6.25%) 5 (41.7%) 0 (0%) 0 (0%) 0.11
Anti SS-A antibodies 1 (11.14%) 6 (37.5%) 2 (16.7%) 0 (0%) 1 (33.3%) 0.53
Anti RO52 antibodies 2 (22.2%) 8 (50%) 5 (41.7%) 0 (0%) 1 (3.3%) 0.63
Anti SS-B antibodies 0 (0%) 3 (18.75%) 0 (0%) 0 (0%) 0 (0%) 0.28
Anti PM-Scl antibodies 0 (0%) 0 (0%) 1 (8.3%) 0 (0%) 0 (0%) 0.65
Anti PCNA antibodies 1 (11.1%) 0 (0%) 1 (8.3%) 0 (0%) 0 (0%) 0.72
Anti dsDNA antibodies 5 (55.6%) 7 (43.75%) 9 (75%) 1 (100%) 0 (0%) 0.13
Anti-Nucleosomes antibodies 0 (0%) 3 (18.75%) 8 (66.7%) 0 (0%) 0 (0%) 0.005*
Anti-Histones antibodies 0 (0%) 2 (12.5%) 4 (33.3%) 0 (0%) 1 (33.3%) 0.29
Anti RP-protein antibodies 0 (0%) 2 (12.5%) 0 (0%) 0 (0%) 0 (0%) 0.51
Anti AMA-M2 antibodies 0 (0%) 0 (0%) 0 (0%) 0 (0%) 1 (33.3%) 0.011*

Ribosomal-P-Protein.  No patients with lupus nephritis had a positive anti Scl-70, JO1 or Centromere B antibodies