Table 1.
Summary of miRNAs including their functions and targets that are discussed in this review.
| miRNA | Target | Function | Species studied | Reference |
|---|---|---|---|---|
| miR-1000 | VGlut | glutamate release, apoptosis | Drosophila | Verma, P., et al., (2015) |
| miR-124 | NA | NMDAR-LTP, spatial learning | Rodent | Yang, Y., et al., (2012) |
| miR-124 | CREB | long-term synaptic facilitation in sensory-motor synapse | Aplysia | Rajasethupathy, P., et al. (2009) |
| miR-124 | GluA2 | calcium-permeable AMPARs and homeostatic plasticity | Rodent | Hou, Q., et al. (2015) |
| miR-124,-9,-34 | NA | spatial learning and working memory | Rodent | Malmevik, J., et al. (2016) |
| miR-125a | PSD-95 | dendritic spine density and dendritic branch | Rodent | Muddashetty, R.S., et al. (2011) |
| miR-125b | GluN2A | dendritic spine morphology | Rodent | Edbauer, D., et al., (2010) |
| miR-128b | RCS | fear extinction | Rodent | Lin, Q., et al., (2011) |
| miR-129 | Kv1.1 | dendrtic regulation of Voltage-gated potassium channel Kv1.1 expression | Rodent | Sosanya, N. M., et al. (2013) |
| miR-132 | p250GAP | synaptic transmission, dendritic spine formation and dendrite morphogenesis | Rodent | Wayman, G. A., et al. (2008), Impey, S., et al. (2010) |
| miR-132 | NA | LTP and LTD in perirhinal cortex, short-term recognition memory | Rodent | Scott, H. L., et al. (2012) |
| miR-132 | NA | short-term synaptic plasticity | Rodent | Lambert, T.J., et al., (2010) |
| miR-132 | Rasa1 | dorsal root ganglion axon growth | Rodent | Hancock, M.L., et al.,(2014) |
| miR-132/212 | NA | basal synaptic transmission and LTP in hippocampus and neocortex | Rodent | Remenyi, J., et al. (2013) |
| miR-134 | Pumilio-2 | dendritic morphology, homeostatic synapse elimination | Rodent | Fiore, R., et al. (2009; 2014) |
| miR-134 | Limk1 | hippocampal dendtic spine morphogenesis | Rodent | Schratt, G. M., et al. (2006) |
| miR-134 | CREB | LTP and contexual fear memory | Rodent | Gao, J., et al. (2010) |
| miR-137 | GluA1 | AMPAR-mediated synaptic transmission, mGluR-LTD | Rodent | Olde Loohuis, N. F., et al. (2015) |
| miR-137 | synaptotagmi n-1 | presynaptic vesicle release, mossy fiber LTP, contextual fear memory | Rodent, human | Siegert, S., et al. (2015) |
| miR-138 | APT1 | morphology of dendritic spines in hippocampal neurons | Rodent | Siegel, G., et al. (2009) |
| miR-146a-5p | Map1b | AMPAR-mediated synaptic transmission, AMPA receptor endocytosis | Rodent | Chen, Y. L. and C. K. Shen (2013) |
| miR-181C | NA | neurite sprouting and synaptogenesis | Rodent | Kos, A., et al. (2016) |
| miR-182 | cortactin, Rac1 | amygdala-dependent long-term memory formation | Rodent | Griggs, E. M., et al. (2013) |
| miR-183/96/182 | HDAC9 | long-term object memory | Rodent | Woldemichael, B.T., et al., (2016) |
| miR-185 | NA | dendrtic spine morphology | Rodent | Xu, B., et al. (2013) |
| miR-188-5p | neuropilin-2 | dendritic spine density, synaptic transmission, | Rodent | Lee, K., et al. (2012) |
| miR-191, miR-135 | Tmod2, Cplx1/2 | NMDAR-LTD and the associated dendritic spine remodeling | Rodent | Hu, Z., et al. (2014) |
| miR-22 | CPEB | long-term synaptic facilitation in sensory-motor synapse | Aplysia | Fiumara, F., et al. (2015) |
| miR-223 | GluN2B and GluA2 | mEPSC, contexual fear memory | Rodent | Harraz, M.M., et al. (2012) |
| miR-26a, miR-384-5p | RSK3 | NMDAR-LTP and the associated dendritic spine remodeling | Rodent | Gu, Q. H., et al. (2015) |
| miR-29a/b | Arpc3 | dendritic spine morphology | Rodent | Lippi, G., et al. (2011) |
| miR-33 | NA | contextual fear memory | Rodent | Jovasevic, V., et al., (2015) |
| miR-485 | SV2A | homoestatic plasticity, dendritic spine density, synaptic transmission | Rodent | Cohen, J. E., et al. (2011) |
| miR-501-3p | GluA1 | dendritic AMPAR expression, dendritic spine remodeling during NMDAR-LTD | Rodent | Hu, Z., et al. (2015) |
| miR-92 | KCC2, CPEB3, MEF2D | contextual fear memory, dendritic spine density | Rodent | Vetere, G., et al. (2014) |
| miR-932 | Act5C | long term memory recall, but not memory acquisition during olfactory learning | Honeybee | Cristino, A. S., et al. (2014) |