Table 2. Logistic regression analysis of association between CAMKK1 rs7214723 polymorphism and risk of LC.
| Genotype | Cases* (n=320) | Controls* (n=320) | OR (95% CI) | P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| TC compared with TT | 122/133 | 38.1/41.6 | 130/149 | 40.6/46.6 | 1.05 (0.75–1.48) | 0.773 |
| CC compared with TT | 61/133 | 19.1/41.6 | 38/149 | 11.9/46.6 | 1.80 (1.13–2.87) | 0.014 |
| CC compared with TC compared with TT | ||||||
| TC + CC compared with TT | 183/133 | 57.2/41.6 | 168/149 | 52.5/46.6 | 1.22 (0.89–1.67) | 0.214 |
| CC compared with TC + TT | 61/255 | 19.1/79.9 | 38/279 | 11.9/87.2 | 1.76 (1.13–2.73) | 0.012 |
| C compared with T | 244/388 | 38.1/60.6 | 206/428 | 32.2/66.9 | 1.31 (1.04–1.65) | 0.023 |
Bold values are statistically significant (P<0.05).
*
The genotyping was successful in 316 cases and 317 controls.