Table 3. Stratified analyses between CAMKK1 rs72114723 polymorphism and the risk of LC.
Variable | CAMKK1 rs72114723 (case/control) | CC compared with TT | CC + TC compared with TT | CC compared with TC + TT | ||
---|---|---|---|---|---|---|
CC | TC | TT | ||||
Sex | ||||||
Male | 54/32 | 105/120 | 87/90 | 1.75 (1.03–2.96); 0.038 | 1.08 (0.75–1.57); 0.675 | 1.85 (1.14–2.98); 0.012 |
Female | 7/6 | 17/10 | 46/59 | 1.50 (0.47–4.76); 0.495 | 1.92 (0.92–4.04); 0.083 | 1.28 (0.41–4.01); 0.674 |
Age (years) | ||||||
<50 | 27/14 | 46/38 | 48/50 | 2.48 (0.72–8.44); 0.153 | 1.46 (0.86–2.49);0.162 | 1.81 (0.89–3.67); 0.102 |
≥50 | 34/24 | 76/92 | 85/99 | 4.39 (0.90, 21.50); 0.067 | 1.10 (0.75–1.63); 0.617 | 1.68 (0.96–2.95); 0.071 |
Smoking status | ||||||
Non-smoker | 5/8 | 10/7 | 66/63 | 0.60 (0.19–1.92); 0.387 | 0.96 (0.43–2.11); 0.909 | 0.58 (0.18–1.84); 0.352 |
Smoker | 56/30 | 112/123 | 67/86 | 2.40 (1.39–4.14); 0.002 | 1.41 (0.96–2.08); 0.082 | 2.18 (1.34–3.55); 0.002 |
Bold values are statistically significant (P<0.05).