Fig. 2.
Endogenous AT3 is present in aggresomes formed by CFTRΔF508. (A) Endogenous AT3 colocalizes with aggresomes formed by CFTRΔF508-GFP in COS 7 cells after proteasome inhibition with MG132 as well as preaggresome particles after nocodazole disruption of microtubules. (B) FLAG-tagged HDAC6 colocalizes with aggresomes and preaggresome particles of CFTRΔF508-GFP.