Table 5.

Multivariable analysis for the association between Severe TIAEs and ICU mortality

Factors	Odds ratio (95% CI)	p-value
Severe TIAEs	1.80 (1.24–2.60)	0.002
Age in year
Infant	Reference
Child (1–7 year)	1.39 (1.06–1.82)	0.02
Older child (8–17 year)	1.77 (1.32–2.39)	<0.001
PIM2 score	1.02 (1.02–1.03)	<0.001
Diagnosis
Respiratory Failure	1.12 (0.77–1.62)	0.57
Neurological (non-TBI)	0.92 (0.57–1.48)	0.74
Cardiac	1.51 (1.00–2.28)	0.049
Sepsis/Shock	1.49 (0.93–2.40)	0.10
Indication for tracheal intubation*
Respiratory Failure	1.31 (1.00–1.72)	0.05
Hemodynamic Instability	1.97 (1.44–2.69)	<0.001
Procedure	0.43 (0.27–0.67)	0.001
Impaired airway protective reflexes	1.31 (0.85–2.00)	0.22
Difficult airway features
Upper airway obstruction	0.54 (0.35–0.85)	0.008

TIAE: tracheal intubation associated events

Total N= 3841

Overall p<0.0001, Pseudo-R2= 0.0732

A multivariable regression model for Severe TIAE included covariates associated with occurrence of severe TIAE (age, diagnosis, indication for respiratory failure, shock, procedural, loss of airway protection, and symptom of upper airway obstruction) and PIM2 score. The association with occurrence of severe TIAE in univariate analysis with p=<0.1 was used for inclusion criteria for multivariable logistic regression model.

^*Patients may have more than one indication for tracheal intubation