. 2017 Jul 11;60(15):6721–6732. doi: 10.1021/acs.jmedchem.7b00671

Table 2. Carmaphycin B and Analogs 1–20 along with Their P. falciparum Asexual Blood Stage Activity and Cytotoxicity toward HepG2 Cells and the Selectivity Index (Comparing the P. falciparum Activity versus HepG2 Activity)^a.

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The residue in the chemical structure that changes compared to the previous group of analogs is colored in red. Results are presented as the mean ± SEM with n = 3.

Table 2. Carmaphycin B and Analogs 1–20 along with Their P. falciparum Asexual Blood Stage Activity and Cytotoxicity toward HepG2 Cells and the Selectivity Index (Comparing the P. falciparum Activity versus HepG2 Activity)a.

Table 2. Carmaphycin B and Analogs 1–20 along with Their P. falciparum Asexual Blood Stage Activity and Cytotoxicity toward HepG2 Cells and the Selectivity Index (Comparing the P. falciparum Activity versus HepG2 Activity)^a.