Skip to main content
. Author manuscript; available in PMC: 2018 Aug 2.
Published in final edited form as: Neuron. 2017 Jul 14;95(3):623–638.e4. doi: 10.1016/j.neuron.2017.06.034

Figure 7. Feedback modulation enables pathway-specific plasticity in developing sensory circuits in Drosophila.

Figure 7

The pathway-specific plasticity of the developing nociceptive circuit in Drosophila is different from the serotonergic facilitation that occurs during sensitization of the defensive gill-withdrawal reflex in Aplysia. In the Drosophila nociceptive circuit, activity in nociceptors (“S”) leads to activation of both SONs in the circuit and serotonergic interneurons (“5-HT”), while in Aplysia gill-withdrawal reflex circuit, serotonergic interneurons are activated by another sensory pathway (S2).