Table 4.
Performance characteristics of the Wayne assay for pyrazinamide susceptibility testing in 223 clinical isolates, using BACTEC™ MGIT 960 as the reference standard.
BACTEC™ MGIT 960 | ||||||
---|---|---|---|---|---|---|
|
||||||
Wayne assay | Total No. |
Resistant No. (%) |
Susceptible No. (%) |
Sensitivity (95% CI) |
Specificity (95% CI) |
Kappa (95% CI) |
Resistant | 82 | 68 (82.9) | 14 (17.1) | 75.6% (65.4–84.0) | 89.5% (83.0–94.1) | 0.66 (0.56–0.76) |
Susceptible | 141 | 22 (15.6) | 119 (84.4) | |||
Total | 223 | 90 (40.4) | 133 (59.6) |
CI=confidence interval; MGIT=mycobacteria growth indicator tube.