Table 2.

EBV genes differentially regulated by I-BET during viral reactivation

Bold font indicates differentially regulated genes with a p value <0.05.

Gene	Coordinates	Log2 -fold change	p value
Late (4 of 18 change expression level)
BNRF1	1691–5407	−0.68	0.038
BCRF1	9631–10262	+0.03	0.929
BOLF1	59905–62728	−0.29	0.485
BORF1	63035–63880	−0.22	0.621
BSRF1	74594–75316	+0.27	0.418
BLRF1	76232–76574	−0.54	0.127
BLLF1	77764–79904	−0.73	0.112
BZLF2	89483–89828	−0.94	0.233
BRRF2	93955–95631	−0.54	0.115
BKRF2	97655–98064	−0.78	0.009
BBRF1	101972–103659	−0.11	0.504
BBRF3	106751–108075	−0.48	0.088
BGRF1/BDRF1	112826–113190, 117017–118064	−0.43	0.008
BDLF1	120189–121018	−0.60	0.333
BcLF1	121099–125072	−0.80	0.075
BXRF1	132847–133012	−0.14	0.611
BVRF2	135628–136330	−0.65	0.095
BILF2	137464–138282	−0.28	0.017
Early (0 of 18 change expression level)
BHLF1	38014–40529	−0.45	0.297
BHRF1	41471–43251	−0.56	0.054
BFLF1	44794–46235	−0.28	0.473
BaRF1	66601–67551	−0.23	0.445
BSLF1a	72069–74593	−0.20	0.578
BLLF3	75320–76218	−0.21	0.458
BRLF1a	90907–92727	+0.07	0.796
BRRF1	92898–93827	−0.10	0.689
BBLF4a	99537–101587	−0.19	0.180
BBLF2/BBLF3a	104503–105098, 105227–106692	+0.10	0.653
BcRF1	125423–127415	+0.04	0.801
BXLF1	131022–132570	+0.22	0.618
LF3	140692–143711	−0.10	0.667
BALF5a	152642–155265	−0.22	0.311
BALF3	160532–160549	−0.59	0.216
BALF2a	160909–164356	−0.38	0.375
BALF1	164388–164984	−0.24	0.356
BARF1	165008–165712	−0.38	0.078
Unassigned (0 of 6 change expression level)
BCLT1	5868–6136	+0.26	0.995
BCLT2	6172–6475	+0.18	0.827
BFRF1A	46281–46543	−0.13	0.794
BGLF3	111830–112649	−0.30	0.348
BDLF3.5	116767–116926	−0.11	0.764
BVLF1	134887–135431	−0.22	0.512

^a Protein product required for lytic DNA replication.