Figure 1.

The 200 × 200 macular cube (Carl Zeiss Meditec, Inc.) consists of 40,000 A-scan measurements that were clustered into a 20 × 20 grid of superpixels centered on the fovea. Local asymmetry measures were defined based on comparison of the GCIPL thickness on the three corresponding pairs of rows above and below the temporal horizontal raphe including four or eight temporal columns, both individually and in combination. The best performing local asymmetry parameter was the one incorporating the three rows above and below the temporal raphe consisting of eight superpixels.