Table 1. NQO1 inducer potencies (CD) and NO synthesis inhibitory activity (IC50) of TP.
Cell type | TP-225 | TP-155 | TP-162 | TP-156 |
---|---|---|---|---|
CD, μM | ||||
Hepa 1c1c7 | 0.00028 | 0.0010 | 0.10 | 1.5 |
MEF | 0.0020 | 0.0060 | 0.14 | 3.0 |
ARPE-19 | 0.0016 | 0.0070 | 0.13 | 2.8 |
RAW264.7 | 0.0030 | 0.0075 | 0.12 | 4.5 |
IC50, μM | ||||
RAW264.7 | 0.00080 | 0.001 | 0.015 | 0.155 |