Table 3. Inducer potencies for NQO1 of TP in Hepa1c1c7 cells and their Bprc1 and c1 mutants.
Cell line | TP-151 | TP-155 | TP-223 | TP-224 | TP-225 | TP-233 | SUL | BNF |
---|---|---|---|---|---|---|---|---|
Hepa1c1c7 | 0.0023 | 0.0010 | 0.0013 | 0.0010 | 0.00028 | 0.22 | 0.23 | 0.023 |
Bprc1 | 0.0052 | 0.0022 | 0.0022 | 0.0028 | 0.00054 | 0.30 | 0.16 | Inactive |
c1 | 0.0080 | 0.0015 | 0.0015 | 0.0024 | 0.00042 | 0.13 | 0.15 | Inactive |
Shown are CD values (μM). SUL, sulforaphane; BNF, β-naphthoflavone.