Table 1. Meal pattern variables measured in Experiment 1.
Data are means ± SEM. In Experiment 1, dark phase meal patterns were analyzed in oil- and EB-treated OVX female rats treated with intra-LV vehicle, 1 μg GLP-1, and 10 μg GLP-1.
| Meal Pattern Variable | Group | GLP-1 Dose | ||
|---|---|---|---|---|
| Vehicle | 1 μg | 10 μg | ||
| Latency to first meal, min | ||||
| Oil | 2.7 ± 1.27 | 0.2 ± 0.13 | 3.1 ± 2.07 | |
| EB | 8.9 ± 4.78 | 62.8 ± 26.80 | 58.5 ± 27.64 | |
| 4 h average meal duration1, sec | ||||
| Oil | 1273.1 ± 162.8 | 1111.8 ± 216.6 | 1404.0 ± 285.4 | |
| EB | 1960.4 ± 561.4 | 1760.6 ± 647.2 | 1403.1 ± 456.7 | |
| 12 h average meal duration, sec | ||||
| Oil | 1657.4 ± 234.3 | 1711.3 ± 453.5 | 1498.5 ± 228.5 | |
| EB | 2341.7 ± 513.8 | 2158.3 ± 496.9 | 1861.0 ± 439.6 | |
| 4 h average IMI2, sec | ||||
| Oil | 6054.1 ± 713.3 | 6435.9 ± 604.0 | 6997.3 ± 712.8 | |
| EB | 4292.1 ± 603.6 | 4857.3 ± 1158.7 | 4754.2 ± 884.8 | |
| 12 h average IMI, sec | ||||
| Oil | 5508.3 ± 313.6 | 5543.8 ± 631.0 | 7275.9 ± 575.7 * | |
| EB | 3864.3 ± 307.4 | 4880.4 ± 452.9 | 4821.2 ± 500.5 | |
IMI = inter-meal interval; sec = seconds. Bolded group identifiers indicate significant main effect of hormone treatment.
*
p<0.05 relative to respective hormone group vehicle condition.
1
Analysis only includes rats that consumed ≥ 1 meal during the first 4 h of the dark phase (n = 10 oil- and 11 EB-treated rats).
2
Analysis only includes rats that initiated ≥ 2 meals during the first 4 h of the dark phase (n = 9 oil- and 7 EB-treated rats).