Skip to main content
. Author manuscript; available in PMC: 2017 Aug 14.
Published in final edited form as: Toxicol Lett. 2017 Jan 16;268:26–35. doi: 10.1016/j.toxlet.2017.01.002

Table 1.

Concentrations of endogenous formaldehyde reported in human blood and cultured human cells.

Biological matrix Method Formaldehyde conc. (μM) N Notes Reference
Whole blood GC-MS 87±4.7 6 Mean±S.D. (Heck et al., 1985)
Whole blood LC-MS 22 1 (Nagy et al., 2004)
Plasma Derivatization + LC-fluorescence 37 (29–45) 2 Median (Range) (Luo et al., 2001)
Nasal epithelial cells Derivatization + fluorescence 3 2 At LOD (Neuss et al., 2010)
Cancer cells SIFTCI-MS 1.3 (0–4) 6 Median (Range) (Kato et al., 2001)
HeLa cells Derivatization + spectrophometry 18 1 (Ke et al., 2014)

GC, gas chromatography; LC, liquid chromatography; LOD, limit of detection; MS, mass spectrometry; SIFTCI, selected-ion-flow-tube chemical ionization.