Figure 2.
IMS profiling of the Aβ(6–16) isomer variants. Individual Aβ(6–16) peptide isomer standards containing L-aspartic acid (L-Asp), D-aspartic acid (D-Asp), L-isoaspartic acid (L-isoAsp) and D-isoaspartic acid (D-isoAsp) were analyzed using a A) 90-cm DTIMS-MS platform and B) 67.5-m SLIM IMS-MS platform. The SLIM IMS-MS platform was also able to baseline separate the isomer mixture allowing accurate quantitation of each peptide (C). The sequence of Aβ(6–16) is provided on the top panel.