(A) Swabs were collected from the lesion, nearby adjacent skin, and contralateral skin sites for 16S rRNA analysis. (B) Bacterial diversity was assessed by the number of observed species-level OTUs and Shannon Index. (C) Bar charts represent intragroup mean Bray-Curtis dissimilarity between each skin site. (D) PCoA values for weighted UniFrac analysis were plotted and colored based on the Dirichilet multinomial cluster assignment. (E) Stacked bar charts represent the proportion of the top 10 taxa present in each Dirichilet cluster. Swabs were collected from an n = 44 patients. **, p < 0.01; ***, p < 0.001; ****, p , 0.0001. See also Figure S1, Table S1, and Table S2.