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. Author manuscript; available in PMC: 2018 Jul 12.
Published in final edited form as: Cell Host Microbe. 2017 Jun 29;22(1):13–24.e4. doi: 10.1016/j.chom.2017.06.006

Figure 2. L. major infection alters the skin microbiota.

Figure 2

C57BL/6 mice were intradermally infected in the ear with 2 × 106 L. major parasites. (A) Lesion size and (B) pathology were assessed over 12 weeks of infection. Swabs were collected from the ear at 0, 6, and 12 weeks post-infection and bacterial diversity was assessed by (C) number of observed species-level OTUs and (D) Shannon Index. Stacked bar charts represent the proportion of the top 10 taxa present (E) from ear swabs and (F) from fecal pellets at 0, 6, and 12 weeks post-infection. Each column represents the proportion of taxa for an individual mouse. Data represent two independent experiments (n = 1 skin swab each from 15 mice and n = 1 fecal pellet each from 10 mice). *, p < 0.05; ***, p < 0.001.