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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Eur J Pharm Biopharm. 2016 Aug 12;108:126–135. doi: 10.1016/j.ejpb.2016.08.005

Table 4. Influence of Apo A–I loading on the prototype HDL-mimicking α-tocopherol-coated NPs (n=3).

Batch 5–6 in Table 3 was modified by changing the contents of PC and Apo A–I to obtain batch 5–8 and 5–9.

Experiment PC
(µg)		 Apo A–I
(µg)		 Particle size
(nm)		 P.I. Loading of Apo A–I
(%, w/w)		 EE% of
Apo A–I
5–6 40 70 145 ± 5 0.289 ± 0.012 43.8 31 ± 5.4
5–8 39 106 152 ± 5 0.265 ± 0.012 54.3 31 ± 3.6
5–9 38 140 156 ± 11 0.273 ± 0.001 61.4 26 ± 2.5