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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Eur J Pharm Biopharm. 2016 Aug 12;108:126–135. doi: 10.1016/j.ejpb.2016.08.005

Table 5. Ion-pair complexes of protamines or poly-D-Lysine with NGF at different ratios.

NGF : Polycation Protamine free base Protamine salt from salmon Protamine sulfate USP Poly-D-Lysine
(w/w) in water Size (nm) Potential (mV) Size (nm) Potential (mV) Size (nm) Potential (mV) Size (nm) Potential (mV)
0.8 : 1 554.3 12.22 278.5 0.34 562.6 0.86 529.3 0.54
1 : 1 863.6 0.58 589.4 0.22 802.6 0.30 805.5 −0.82
1.2 : 1 596.4 −0.71 543.7 0.59 356.0 −0.32 830.0 −4.53